Blastomycosis

BLASTOMYCES DERMATITIDIS (BLASTOMYCOSIS) AIRBORN TRANSMISSION PRIMARILY PULM MANIFESTATIONS–75% NODULAR INFILTRATES ON CXR CAN CAUSE LESIONS ANYWHERE IN THE UPPER AERODIGESTIVE TRACT LESS LIKELY THAN HISTO TO CAUSE EXTRA PULM LESIONS SKIN LESIONS= SHARPLY DEMARKATED RAISED MARGINS WITH CENTRAL SCARRING PSUEDOEPITHELIOMATOUS HYPERPLASIA—-MULTIPLE MICROABSCESSES PRIMARILY GLOTTIC LARYNX BROAD BASED BUDS GROWS ON SABOURAD’S MEDIUM CAN Dx BY IMMUNE SEROLOGY Rx AMPHO B FOR LIFE THREATENING Dz OR ITRACONAZOLE 400 MG Q D FOR 6 MO

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