CHURG-STRAUSS SYNDROME(EOSINOHILIC ASTHMA)—Described by Jacob Churg and Lotte Strauss in 1951

ALLERGIC ANGIITIS–A MULTISYSTEM GRANULOMATION VASCULITIS

LIKE A COMBINATION OF RELAPSING POLYCHONDRITIS AND ASTHMA

CAN BE UNMASKED BY NEW ANTI-LEUKOTRIENE ASTHMA MEDS

50% 5 YEAR SURVIVAL

FEMALE 1.3:1 MALE

3 STAGES:

PRODROMAL: RHINITIS, NAO, BRONCHIAL ASTHMA (LUNGS ARE ALWAYS INVOLVED)

HYPEREOSINOPHILIC PHASE

WIDE SPREAD (SYSTEMIC) VASCULITIS

ANCA – (A CLINICAL Dx)

Rx: STEROIDS