Adjuvant therapies I have found useful in diminishing the recurrence of this frustrating disease. Use the CO2 laser. Have patients eat green leafy vegetables (Indole-3-carbinols) modulates estrogen metabolism and 1/3 of patients respond. Inject Cidofovir after resection. Place on Celebrex (Cox 2 inhibitor) modulates the over expression of epidermal growth factor by inhibiting cyclooxygenase-2 and prostaglandin E2. Give Gardisil (6,11,16,18). Consider injecting Avastin (Bevacizumab) recombinant monoclonal antibody against vascular endothelial growth factor. And, of couse prayer!