CHURG-STRAUSS SYNDROME(EOSINOHILIC ASTHMA)—Described by Jacob Churg and Lotte Strauss in 1951
ALLERGIC ANGIITIS–A MULTISYSTEM GRANULOMATION VASCULITIS
LIKE A COMBINATION OF RELAPSING POLYCHONDRITIS AND ASTHMA
CAN BE UNMASKED BY NEW ANTI-LEUKOTRIENE ASTHMA MEDS
50% 5 YEAR SURVIVAL
FEMALE 1.3:1 MALE
3 STAGES:
PRODROMAL: RHINITIS, NAO, BRONCHIAL ASTHMA (LUNGS ARE ALWAYS INVOLVED)
HYPEREOSINOPHILIC PHASE
WIDE SPREAD (SYSTEMIC) VASCULITIS
ANCA – (A CLINICAL Dx)
Rx: STEROIDS