MUCORMYCOSIS IMMUNOCOMPROMISED HOST(AIDS), NEUTROPENIA,  AND OR DKA(ACIDOSIS AND HYPOGLYCEMIA), DEFEROXIMINE LOW GRADE FEVER, DULL SEVERE SINUS PAIN, EPISTAXIS, FACIAL HYPESTHESIA——DIPLOPIA, OBTUNDATION, FEVER, BLACK TURBINATES, PROPTOSIS, FACIAL SWELLING, BLINDNESS—-COMA—-DEATH PAY SPECIAL ATTENTION TO THE MIDDLE TURBINATE! Rx = EARLY DIAGNOSIS—SUSPICION, BIOPSY—BRANCHING(90 DEGREES) AT RIGHT ANGLES, THICK WALLED NON-SEPTATE HYPHAE “M”—DEBRIDE–RADICAL MAXILLECTOMY, ORBITAL EXENTERATION, AMPHO B LIPOSOMAL —IRRIGATIONS, SYSTEMIC AMPHO B AND HBO! STAIN + WITH HMB-45 (MELANIN STAIN) CONSIDER GRANULOCYTE STIM FACTOR—THEIR RESPONSE PARALLELS THEIR SURVIVAL

The hyphae of the mucoraceous zygomycetes have a characteristic appearance in tissue sections.  Typical hyphae are broad (6 to 25 micrometer wide), thin-walled and pleomorphic, with irregular, non-parallel contours.  Branches arise haphazardly, often at right angles to the parent hyphae. Septa can be found in some of the hyphae, though most of the hyphae appear nonseptate (cenocytic).  Because the hyphae have little structural stability, they are often folded, twisted, wrinkled, or collapsed.  The thin hyphal walls stain as well with hematoxylin as with the special stains for fungi.