MENINGIOMA
USUALLY OF THE ARACHNOID CELLS (ARACHNOID CELL CLUSTERS WITHIN THE DURA)
USUALLY ADJACENT BONEY HYPEROSTOSIS
= 20% OF CNS NEOPLASMS
ONLY 2% ECTOPIC
2/100,000, FEMALE 2:1, INCREASED INCIDENCE WITH AGE AND RT EXPOSURE
PRIMARILY MET TO LUNGS
INCREASED ASSOC. WITH NF
CLASSIC PATH: PSAMMOMA BODIES (LIKE PAPILLARY THYROID CA)
FOUR HISTO PATTERNS: SYNCYTIAL(POSYGONAL), TRANSITIOAL(PSAMMOMATOUS), FIBROUS, ANGIOBLASTIC
+ S-100, VIMENTIN, EMA(EPITHELIAL MEMBRANE ANTIGEN)
Rx—-SURGERY, RU-486 (PROGESTERONE INHIBITOR) MAY HELP
FOSTER-KENNEDY SYNDROME(SPHENOID MENINGIOMA OF THE OLFACTORY OR OPTID GROOVE)
IPSI OPTIC ATROPHY–MARCUS GUN PUPIL
CONRALATERAL PAPILLEDEMA (ICP FROM MASS EFFECT)
CAN PRESENT WITH ATYPICAL BEHAVIOR AND PERSONALITY CHANGES AND ANOSMIA/PAROSMIA